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Drug interactions could improve how your prescription drugs function or increase your hazard for major Unintended effects. This document isn't going to comprise all doable drug interactions.
Advise feminine individuals of reproductive likely that prolonged use of oxycodone and acetaminophen tablets during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening Otherwise acknowledged and taken care of [see WARNINGS, PRECAUTIONS; PREGNANCY].
Clients The use of PERCOCET in individuals with acute or severe bronchial bronchial asthma in an unmonitored setting or in the absence of resuscitative gear is contraindicated.
Loop Diuretics The consequences of the loop diuretic may very well be diminished for the reason that acetaminophen could minimize renal prostaglandin excretion and decrease plasma renin activity.
Accidental ingestion of oxycodone and acetaminophen tablets, In particular by kids, can lead to respiratory melancholy and Loss of life on account of an overdose of oxycodone and acetaminophen tablets.
Carbon dioxide (CO2) retention from opioid-induced respiratory depression can exacerbate the sedating results of opioids. Even though really serious, everyday living-threatening, or deadly respiratory despair can occur Anytime all through the use of PERCOCET, the chance is finest through the initiation of therapy or following a dosage enhance.
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Notify patients that oxycodone and acetaminophen tablets may well impair the opportunity to perform most likely dangerous actions such as driving an automobile or working hefty equipment. Recommend clients not to perform such jobs till they know how they'll react towards the medication [see PRECAUTIONS].
Tell feminine individuals of reproductive likely that oxycodone and acetaminophen tablets may cause fetal damage and to inform the healthcare service provider of a known or suspected pregnancy [see Safeguards; PREGNANCY].
PERCOCET shouldn't be supplied into a pregnant woman Except from the judgment of your physician, the potential benefits outweigh the probable dangers.
Get rid of expired, undesired, or unused PERCOCET by immediately flushing down the toilet, if a drug get-back alternative is just not readily available. Pay a visit to for additional information on disposal of unused medicines.
The abnormal consumption of acetaminophen might be intentional to bring about self-damage or unintentional as patients try to obtain additional suffering aid or unknowingly choose other acetaminophen-made up of products and solutions.
Oxycodone and acetaminophen tablets are contraindicated in individuals with acknowledged or suspected gastrointestinal obstruction, including paralytic ileus.
Following halting a CYP3A4 inducer, as the effects in the inducer drop, the oxycodone plasma concentration will maximize [see Scientific PHARMACOLOGY], which could enhance or prolong equally the therapeutic results and adverse reactions, and should lead to major respiratory depression.